Here are some recommended sister-brother romance novels with male and female protagonists:
1. "獨愛驕陽" - This novel features a sister-brother romance set in a wealthy family, with a dramatic conflict-filled love story.
2. "竹馬他蓄意已久" - This novel combines a childhood friends trope with a sister-brother romance, showcasing the pure and deep love between the main characters.
3. "君生我已老" - This novel tells the story of a female protagonist who takes care of a male protagonist, leading to a seven-year age gap romance. Despite facing obstacles, their love eventually prevails.
4. "水族館冷艷火" - In this novel, a beautiful and talented female protagonist falls in love with a male protagonist who becomes clumsy and nervous around her. They navigate their complicated relationship without interference from others.
5. "偏執(zhí)弟弟是大佬" - This sweet story revolves around a sister-brother romance, with the male protagonist being possessive and obsessed with the female protagonist.
Please note that these recommendations are based on the provided search results and may not reflect personal preferences or opinions.